Even though the opiate receptor relies on G protein coupling for signal transduction, this receptor was observed to make use of arrestin activation for internalization from the receptor. Or else, the receptor promoted no other signaling cascades (59) Modifications of conolidine have resulted in variable enhancement in binding efficacy. https://isconolidineanopiate68668.free-blogz.com/76593439/detailed-notes-on-bennifits-of-conolidine