Increased activation of essential oncogenic signalling pathways (PI3K/AKT, RAS/MAPK and MYC) upstream of ribosome biogenesis constitutes yet another hallmark of HGSC,9 and we hypothesise that inhibiting ribosome biogenesis can offer a powerful cancer therapeutic solution.10 In truth, We've got demonstrated encouraging responses with the ribosomal RNA gene (rDNA) transcription inhibitor https://nadolol57801.dbblog.net/5031686/detailed-notes-on-nadolol