Epidural clonidine applied as an adjunct to local anesthetics has a few unique mechanisms of action. First, the stimulation of alpha-two-receptors within the dorsal horn lessens suffering transmission. Secondly, clonidine can cause community vasoconstriction that limits vascular removal of community epidural anesthetics. : connected to, served by, or available https://what-is-conolidine21909.p2blogs.com/31243721/onolidine-fundamentals-explained