Normally this pressure is 0.twenty five inches of drinking water column, but is usually lifted or decreased as the method needs. Isolators should be periodically leak tested to be sure their integrity and stop escape in the decontamination agent. Leak testing can be achieved by a variety of methods https://tailinscitech.wixsite.com/tailinscitech/post/applications-and-benefits-of-tailin-containment-isolator-for-handling-high-potency-materials