Pentobarbital will reduce the extent or outcome of diltiazem by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or impact of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. pentobarbital will minimize the level or outcome of ombitasvir/paritaprevir/ritonavir & dasabuvir... https://troymnxwv.tinyblogging.com/the-single-best-strategy-to-use-for-pentobarbital-sodium-overdose-65251503